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8 may 2006

A previous note regarding the influence of regular exercise on adiponectin levels in women with metabolic syndrome

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The present study was designed to determine the influence of regular exercise on plasmatic adiponectin levels in women with metabolic syndrome. To get this goal, sixty young women with metabolic syndrome according to the criteria reported by the National Cholesterol Education...

 
Autor(es): Fornieles G, Rosety I, Rosety MA, Macias-Amat IM, Ordóñez FJ, Rosety-Rodríguez M.
Entidades(es): ESCUELA MEDICINA DEL DEPORTE. UNIVERSIDAD DE CADIZ
Congreso: II Congreso Internacional de las Ciencias del Deporte
Pontevedra:08-10 de Mayo de 2006
ISBN: 978-84-612-3518-6
Palabras claves: Metabolic syndrome; Exercise; Adiponectin

RESUMEN COMUNICACIÓN/PÓSTER

The present study was designed to determine the influence of regular exercise on plasmatic adiponectin levels in women with metabolic syndrome. To get this goal, sixty young women with metabolic syndrome according to the criteria reported by the National Cholesterol Education Program Adult Treatment Panel III volunteered for this study. Fourty five were randomly included in experimental group to perform a 12-week aerobic training program, 3 days/week, consisting of warm up (10 min), main part (20-35 min [increasing 5 minutes each three weeks]) at a work intensity of 60-75% of peak heart rate (increasing 5% each three weeks) and cool-down (10 min).   Control group included 15 age, sex and BMI-matched women with metabolic syndrome that will not perform any training program. Plasma adiponectin was assessed using a commercially available radioimmunoassay kit (HADP-61HK) 72-hours before starting the program (pre-test) and after its ending (post-test). When compared to baseline IL-6 levels were decreased significantly after being exercised (5.9±2.4 vs 8.2±2.7 pg/ml; p<0.05). On the contrary no changes were reported in controls. It may be concluded regular exercise may increase plasmatic adiponectin levels in women with metabolic syndrome. Further studies on this topic are required.

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Introduction

Recent studies have reported physical activity may improve adiponectin levels in obese laboratory animals. On the contrary little information is available in humans. The present study was designed to determine the influence of regular exercise on plasmatic adiponectin levels in women with metabolic syndrome.

Methods:

Sixty young women with metabolic syndrome according to the criteria reported by the National Cholesterol Education Program Adult Treatment Panel III volunteered for this study. Fourty five were randomly included in experimental group to perform a 12- week aerobic training program, 3 days/week, consisting of warm up (10 min), main part (20-35 min [increasing 5 minutes each three weeks]) at a work intensity of 60-75% of peak heart rate (increasing 5% each three weeks) and cool-down (10 min). Control group included 15 age, sex and BMI-matched women with metabolic syndrome that will not perform any training program. Written informed consent was obtained from all participants. Further our protocol was approved by an institutional ethic committee. Plasma adiponectin was assessed using a commercially available radioimmunoassay kit (HADP-61HK) 72-hours before starting the program (pre-test) and after its ending (posttest).

Results:

When compared to baseline IL-6 levels were decreased significantly after being exercised (5.9±2.4 vs 8.2±2.7 pg/ml; p<0.05). On the contrary no changes were reported in controls.

Conclusion:

It may be concluded regular exercise may increase plasmatic adiponectin levels in women with metabolic syndrome. Further studies on this topic are required.

 

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